EndoCannabinoid Deficiency

Some bodies never produce enough endocannabinoids.  Some bodies are constantly agitated and unable to repair damage.  Some bodies have chronic pain and spasms.  Some bodies could just barely manage until injury or aging pushed them into constant endocannabinoid deficiency.

Similar to a diabetic that does not produce enough insulin, if your body does not produce enough Endocannabinoids, then you need Plant Cannabinoids. People with damaged or weakened production of endocannabinoids need Medical Cannabis. This concept and condition is called Clinical Endocannabinoid Deficiency.  Dr. Ethan Russo’s publication of  Clinical Endocannabinoid Deficiency in 2004 is why Medical Cannabis works for so many conditions.

CECD seems most prevalent with neurological-autoimmune conditions include Multiple Sclerosis, Parkinson’s Disease, Tourette Syndrome, and Fibromyalgia, Cancer, Arthritis, Nerve Damage, Muscle & Joint Pain, Spasms, and Sleep Disorders.  In all these conditions, the body is always moving toward an off-centered, stressed state.  No matter what drug, counseling, physical therapy or nutrition is used, the benefit only lasts a short time before the symptoms return.

Most MMJ patients have CECD issues to some extent.  Only patients with CECD seek non-psychoactive cannabinoids.   Some injury and headache patients do not seem to be the CECD, because they do not benefit from non-psychoactive cannabinoids. Every Medical Stoner Knows they have CECD even if they have never heard of it.- Everyone that use marijuana regularly knows something is physically wrong with them.

In 1992, the late Dr. Richard W. Noble, MD (while treating Green Man Dan) observed that marijuana helped many conditions.  Dr. Noble understood cannabinoids were unique molecules that managed repair and wellness.  Dr. Noble speculated that 20-30 percent of the population had ‘an endocannabinoid deficiency’ requiring plant cannabinoids as a treatment.  Dr. Noble felt that David E. Comings, M.D. (Tourette Syndrome and Human Behavior) correctly linked many conditions to a common genetic issue which Dr. Coming could not identify.   Dr. Comings links Tourette’s, Anxiety, Autism, ADHD, OCD, Depression, Eating Disorders, Hyperactivity, Stuttering, Tics and more.  Dr. Noble agreed with the link Dr. Comings identified but felt CECD was the common issue rather than Comings’ controversial perspective outlined in The Gene Bomb. Furthermore, he felt conditions such as Multiple Sclerosis and Parkinson’s were also related to a lack of cannabinoids.  Dr. Noble felt Cannabis, Nutrition and Diet were the basis of wellness with all these conditions

From Dr. Ethan Russo’s publication of Clinical Endocannabinoid Deficiency (CECD) in 2004, a Google search of ‘Clinical Endocannabinoid Deficiency’ shows the wide support for the concept of CECD.

Genetic research on CECD would be a complex undertaking.  CECD may arise from several different genetic combinations, not just one gene or sequence of genes.  Patient testimonials followed by some clinical studies, will probably be important for validating the concept of CECD.